Gene-Gene Cooperativity in Small Networks
نویسندگان
چکیده
منابع مشابه
Gene-gene cooperativity in small networks.
We show how to construct a reduced description of interacting genes in noisy, small regulatory networks using coupled binary spin variables. Treating both the protein number and gene expression state variables stochastically and on equal footing, we propose a mapping that connects the molecular level description of networks to the binary representation. We construct a phase diagram indicating w...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2009.03.005